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ea0028p171 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2012

Arterial stiffening and increased pressure wave reflection in HIV recipients of highly active antiretroviral therapy (HAART): the influence of insulin sensitivity, adipokines and autonomic nerve function

Bunce Susan , Sinclair Daivd , Smith Jamie

Background: Treatment of HIV patients with antiretroviral therapies may confer an increased cardiovascular risk, possibly mediated through metabolic perturbations induced by these therapies. We sought to determine whether large arterial stiffening, an early marker and predictor of cardiovascular disease, occurs in HIV recipients of HAART, and if so the plausible mechanisms involved.Methods: In this case-control analysis, 56 HIV subjects (mean age 46 &#17...

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Endocrine Abstracts

Arterial stiffening and increased pressure wave reflection in HIV recipients of highly active antiretroviral therapy (HAART): the influence of insulin sensitivity, adipokines and autonomic nerve function

BiosciAbstracts